New at-home spit test for prostate cancer could be better than blood t


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A new spit test for prostate cancer which can be done at home may be better than current testing methods, a study suggests.

Experts have developed a simple saliva test which analyses genetic variants in a man’s DNA, which appears to perform better than the current method for assessing prostate cancer risk.

Currently, the prostate-specific antigen (PSA) blood test is used to check for prostate conditions, including prostate cancer or an enlarged prostate.

Routine testing is not currently available on the NHS, but patients may be offered a PSA test if a GP suspects they have prostate cancer. Men over 50 can ask their GP for a PSA test even if they do not have symptoms.

But experts have said the new saliva test could be used as an additional screening tool, as it reduced the number of false positive results and detected a higher proportion of aggressive cancers than the PSA test.

It could lead to fewer men being sent for unnecessary testing, according to researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust.

They tested the effectiveness of a new tool they had developed called a polygenic risk score, which uses spit to assess 130 genetic variants known to be associated with an increased risk of prostate cancer, which can then determine whether or not a person is at high risk of the disease.

Image:
The new spit test for prostate cancer. Pic: PA

Test saved lives of two brothers

Taking part in the trial saved the lives of two brothers.

Dheeresh Turnbull said traditional methods to assess prostate cancer deemed he had a low risk of disease, but the new spit test helped the 71-year-old discover he actually had a life-threatening tumour in his prostate.

After finding out the news, his brother Joel Turnbull also took part in the study and discovered he had an aggressive prostate tumour.

“It’s incredible to think that because of this study two…

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